An Amazon cargo plane arriving from San Juan, Puerto Rico, overran a runway at Miami International Airport on Sunday and ignited after hitting vehicles, killing at least five people and wounding five others, according to Miami-Dade County officials.

The aircraft went off the runway around 2 p.m., crossed a road used by workers at nearby warehouses and businesses, and struck vehicles before catching fire, officials said at a news conference.

Officials said three of the injured were in critical condition and two others had less severe injuries. They added that it was not yet known whether the people killed were aboard the aircraft or in the vehicles.

The accident sent thick black smoke billowing into the sky over the airport.